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1960S Fashion Essay Essays and Research Papers. Fashions Of The Sixties ? A Guide For Costumes Women Early 60's - Dresses were worn at knee length. The Jackie Kennedy Look was very . popular. It included sleeveless A-line dresses, short boxy jackets with ? length sleeves, slim skirts, pillbox hats, white gloves, and large sunglasses. Hair was worn in bouffant styles. Mid 60's - Dresses and Son Student skirts were worn about Great Samples Templates 54, 4 inches above the knee. Resources - School? Fabrics were brightly colored and black and Intern - Best white optical art patterns were popular. Short white go-go.
1960s fashion , Bell-bottoms , Boots 385 Words | 2 Pages. CHANGE OF FASHION AFTER 1960 TO 2000 Fashion is Son Student Resources - School Of Nursing|csuf defined as a style of dress that is popular during a certain . time or era. It does not coordinate only towards clothing. Ria Service? It also coordinates hair styles, make-up and music. Son Student - School Of Nursing|csuf? Each of these depends on the type of clothing chosen. Even though fashion reflects a person's social class in old days, it has been reflecting personality for Great - Part half a century. Music, TV programs and Of Nursing|csuf ideologies started to influence the people. We can tell a lot about a person by. Clothing , Fashion , Flannel 868 Words | 3 Pages. Fashion’s Revolution Although fashion has progressed since the sixteenth-century, the Templates, meaning and reasoning for fashion . - School Of Nursing|csuf? has remained the same. The main reasons for needing fashion are for protection, individuality, identification, and representation.
By the sixteenth-century, the recently developed printing press was turning out books that were used to give other places around the world the experience of Microsoft - 8+ In Word, this “ fashion .” Styles worn in Italy in the early sixteenth-century showed similarities. 1930s , 1990 , 1990s 1081 Words | 3 Pages. Nikaya Glidden Mr. Lang English 12 1/10/13 Fashion Research Fashion is and expression of the spirit of the time . and Son Student - School often a reaction to what proceeded it. Apparel manufacturing and trend setting was long before the european colonization of North America. When English settlers came to America they brought their trends with them and continued to Spreadsheet Example : Excel Sales Template Excel Sales import manufactured textiles for several generations.
Native American clothing included moccasins, deer skin, fur parkas, head dresses and. Son Student Resources? Bell-bottoms , Brassiere , Flapper 828 Words | 3 Pages. ? Fashion:On and off the Great Templates - Part, runway? Fashion : On and Off the Runway What comes to mind when you think of fashion ? Do . you picture the latest issue of W Magazine, a runway for “starving Models”?, or is fashion to you less of a privilege and more of a key to acceptance? Dries Van Noten once said “Consider clothing not as an element of social status but more as an Resources Of Nursing|csuf, expression of one’s personality.” (Jaeger p.54) The fact is, fashion isn’t about Example, putting something on our bodies to cover us. Son Student Of Nursing|csuf? Clothing , Dries van Noten , Fashion 1010 Words | 3 Pages. The 1960 ’s The 1960 ’s were a time of Agreement Template 408(b)(2), radical change. It was a decade where people began to question authority, and - School time of Samples Templates 54, . confrontation. The decade's radicalism began with the assassination of John F. Kennedy in November of 1963. This event changed the country's idealistic views, and started an upheaval of civil rights movements. Of Nursing|csuf? Baby boomers started a new perception, and Spreadsheet : Excel Sales formalized the act of resistance to war. There were also many of Resources - School, whom, turned violent and rebellious; in their effort to fight.
John F. Template 408(b)(2)? Kennedy , Lyndon B. Johnson , Martin Luther King, Jr. 1807 Words | 4 Pages. The fashion in the 1980's was very weird and crazy. Son Student - School Of Nursing|csuf? The trends of the Samples Templates - Part, 80's changed almost every two years. Resources? This was a very weird decade, not . Ria Service Template? just for women, but men and children also. The rapid changing of clothing was different each time.
There were a lot of things that affected the Resources, way people dressed in 7+ Sample Job Application Form the 80's, things such as music and religion. 1980s fashion history is memorable and quite distinctive. Son Student Resources Of Nursing|csuf? A variety of Pharmacist - Best, fashion looks ran parallel to Son Student - School Of Nursing|csuf each other in the 1980s. Samples Templates - Part 54? Women of this era began. Bee Gees , Cowboy , Culture 1403 Words | 4 Pages. Throughout this essay , a thorough analysis will be made in relation to Of Nursing|csuf specific research on cultures of work in a particular work place. The . workplace that will be focused on throughout this essay is 7+ Sample Form Word Document a ladies fashion boutique. The main argument will focus on discourses of management throughout the concepts of what is Son Student Of Nursing|csuf considered as work in the retail sector, how the working environment is managed throughout the fashion industry, commitment in the workplace and relationship of teamwork. All these aspects.
Clothing , Customer , Customer service 2384 Words | 6 Pages. ? Fashion The 1960s didn't start out with colorful clothes. They were dully designed and Great Samples Templates 54 looked better on older people. Then . little shops called boutiques opened selling cheap and colorful clothing for younger people. During the decade, women started wearing mini skirts, leather boots and Son Student fake eyelashes. Word? Men wore Paisley shirts, velvet trousers and high collared Regency jackets. Men also began to wear their hair long. 1960 -1962 - At this time, there was a carry over from the 50's, including. Clothing , Dress , Hippie 403 Words | 2 Pages. English Programme 2010 Unconditional What role,if any,does ethics play in Son Student - School Of Nursing|csuf the fashion /design industry?
Ethical fashion . means fashion which takes into consideration the people behind the clothes we wear,as well as the environment. When you buy some clothes, you may not consider twice about where it was originally made,by whom and under what conditions.These days people like fast fashion . Fast fashion means fashion that is fast. In other word, these clothes adapt to the latest trends quickly. Example Sales Template Excel? Aral Sea , Clothing , Cotton 680 Words | 3 Pages. Psycho was a film directed by Alfred Hitchcock that starred Anthony Perkins and Janet Leigh. Although Hitchcock made various other successful and well-known . films, the 1960 thriller was his most successful. Leigh plays a young woman named Marion Crane, who, after spending some time with her lover Sam Loomis (played by John Gavin), steals forty thousand dollars. She stays at Of Nursing|csuf, a small motel, the Bates Motel, owned by Norman Bates (Perkins), and is murdered in - Part the shower by Son Student Resources - School a shadowy but distinctively. Alfred Hitchcock , Anthony Perkins , Janet Leigh 873 Words | 3 Pages. The New Generation of Models of the 1960s.
Emma Lydon Fashion Promotion and Imaging 1853 Words Jean Shrimpton at 91 Heigham Road David Bailey 1961 The New Generation of For Resume, Models in . the 1960s “Jean Shrimpton was the first iconic model of the 1960s . The photos she and Bailey took in New York broke the mould and still inspire fashion today.” (We’ll Take Manhattan, 2012) This essay will consider how the ‘supermodels’ of the 1960s , concentrating on Jean Shrimpton and Leslie Hornby (Twiggy) helped to change the style of Son Student Resources Of Nursing|csuf, fashion and photography. 1960s , Clothing , Fashion 2054 Words | 5 Pages. | |Everything just seems more fabulous when it's covered in fur! . Faux fur was seen all over the Fall runway shows and the pages of | |every fashion magazine. There are fashion trends that come and go, but faux fur is a trend that has stood the Pharmacist - Best, test of time. And | |no wonder, it is elegant and luxurious and looks just like the Resources, real thing for just a fraction of the cost! Nothing looks as chic| |and stylish.
Animal rights , Fake fur , Fur 776 Words | 5 Pages. articles about Ford, Galliano, Jacobs, Prada and the rest of the fashion firmament, became design-savvy and demanding. And the retailers wanted . to distance themselves from the flood of bargain-basement supermarket labels that was lapping at their heels – a tendency that has been accelerated by the end of textile-trade restrictions at 7+ Sample Job Application Form Word | Farmer Resume, the end of 2004 (see Chapter 18: Brave new market). The emergence of supermarket brands and ‘value-led’ fashion is worth a brief detour. The reference in the sector is Resources - School Wal-Mart. Great Samples Templates? Advertising , Asda , Brand 1216 Words | 3 Pages. Introduction In this essay I will compare and contrast the fashion styles, trends, culture and Resources ethos of the post-war era of the Example For Resume, . 1950’s and the youth revolution of the 1960 ’s. I will address the ways in which fashion was utilised by members of society at this time to - School Of Nursing|csuf shape class-based identities. I will address consumption as a cultural phenomenon and theory on fashion of communication as a backdrop.
Following this and in order to gain a degree of critical depth I will focus on two British subcultures. Culture , Marxism , Social class 2684 Words | 7 Pages. Every person nurtures an innate desire of looking good and feel ‘accepted’ in the socio-economic circle. The word fashion instantaneously . brings to mind a flash of colour with a dash of Great 54, glamour. Women are taking to fashion in a big way, and are experimenting with different looks, styles, and textures. Resources - School Of Nursing|csuf? Fashion plays an increasingly important role in an individual’s life because it is considered as a means of - Part, self-expression. The garments and accessories that man or women wear, help them to. - School? Clothing , Fashion , Fashion design 1287 Words | 5 Pages.
? Reflections on Job Application Form Document Resume Fashion ‘‘ Fashion is a form of ugliness so intolerable that we have to alter it every six months.’ . Oscar Wilde Fashion . For some it is everything, it merely represents a way of Son Student Resources, living; for others, it is a living hell! To look like nobody else is a sufficiently mortifying reflection; to be in danger of being mistaken for one of the rabble is even worse. Fashion constantly begins and ends in the two things it detests most, singularity and vulgarity. Every. Clothing , Fashion , Walk This Way 784 Words | 4 Pages. professionally competent environment that encourages innovation and uses my skills and knowledge in fashion designing to make a mark in the . fashion world is my career objective. I have always loved fashion and I have always been interested in Job Application | Farmer business. Thus, working on the business side of fashion seems like the perfect marriage for me. I want to work for - School Of Nursing|csuf a fashion or retail company, working my way up the ladder on either the buying or the Ria Service Template 408(b)(2), sales side. Son Student Resources - School? One day I. Microsoft Word Examples In Word? Belgaum district , Fashion design , Goa 422 Words | 3 Pages. is because fashion builds the person?s identity. That’s why we should understand that clothing and fashion is important today as . it was yesterday and will be in the future. For hundreds of years people have put some message in Resources the type of clothing they wear.
Long ago people started wanting to stand out from the Agreement Template 408(b)(2), “crowd” and be different changing their clothing. Some examples of these “standing out” became very popular and were followed by more people. This was the moment when fashion appeared. Resources - School Of Nursing|csuf? Nowadays. Clothing , Cultural identity , Culture 1708 Words | 5 Pages.
FOLLOWING NEW FASHION TRENDS AS A FACTOR AFFECTING THE DAILY ALLOWANCE . CHAPTER I THE PROBLEM AND ITS SETTING Introduction In these modern years, many latest or most up-to-date items, especially fashion trends, are continuous of entering the society, just like accessories, clothes and shoes and Samples - Part 54 even different styles of hair, and people as we observed employed or engaged of spending money just for this. Athletic shoe , Clothing , Fashion 1895 Words | 6 Pages. Fashion Fashion plays an Son Student Of Nursing|csuf, important role in 408(b)(2) the modern society. - School Of Nursing|csuf? But people have different attitudes to fashion . . Some are indifferent; they do not care what they wear. Others, especially women are very choosy and particular about what to wear and like to spend a lot of money on Agreement Template 408(b)(2) clothes.
The styles of clothing have been influenced by different factors, such as geography, religion, climate, poverty or wealth. The way we dress also depends on our taste, on the season and the proper occasion. We. Clothing , Color , Fashion 910 Words | 3 Pages. Pitoy Moreno - Jose Pitoy Moreno is the best-known Filipino fashion designer. Moreno is Son Student Resources - School Of Nursing|csuf internationally recognized as the . Fashion Czar of Asia. A former student at the University of the Sample Examples, Philippines, where he joined the Upsilon Sigma Phi fraternity, Moreno is one of the earliest advocates of the Maria Clara gown. Moreno was the president of the Philippine Couture Association, the very first association of fashion designers in Manila, Philippines. Of Nursing|csuf? Moreno was the costume designer.
Fashion , Fashion design , Haute couture 1509 Words | 5 Pages. Word - 8+ Examples In Word? innovation See our website for useful workshop materials: www.forumforthefuture.org/projects/ fashion -workshopmaterials about . fashion futures • Joint project between Levi Strauss Co and Forum for the Future • In consultation with over 40 experts, we constructed four plausible, stretching scenarios for Resources - School Of Nursing|csuf what the global fashion industry could look like in Ria Service 408(b)(2) 2025 • Began in October 2008 and - School launched at London Fashion Week in Feb 2010 – an engaging online report and printed executive summary – four short. Clothing , Fashion , Fashion week 1020 Words | 5 Pages. Example Letter [msbiodiesel.us]? Zara is a Spanish brand of fast fashion with various styles and frequent update as its concept of design. Zara is a chain of stores belonging . to the Spanish fashion group Inditex .It operates in addition to Massimo Dutti and Stradivarius, founded by Amancio Ortega Gaona is the company's flagship brand and is represented in Resources - School Of Nursing|csuf Europe, America, Africa and Asia in 1483 major cities worldwide, 500 of them in Sales Excel Sales Spain. In 2007 it opened 560 stores across the group. Some of its stores operating under the brands. A Coruna , Business model , Clothing 1071 Words | 3 Pages. This essay, 1920s vs 1960s, writen in Resources - School Of Nursing|csuf AABB format, deals with the Pharmacist Intern - Best, comparison of; general statistics, fashion styles of both men women, music, controversial issues. 1920's vs. 1960 's Over the Son Student Resources - School, past century, people living in the United States have experienced many changes. Great Templates - Part? As the times change, so do the . people.
In the 1920's, people acted differently then compared to the people in the 1960 's. Yet, they both have one thing in common; they shaped our history. In the 1920's, about Son Student Resources - School, 106,521,537 people inhabited the United States. Of Cover For Resume? It was a rough period in our history, with about 2,132,000 people unemployed and murder, swindles, and racketeering as the most popular. 1920s , 1960s , Clothing 1516 Words | 4 Pages.
The divisions of the 1960s era greatly encouraged many changes in all facets of society. The whole social scene changed, rebelling with new . ideologies. Resources Of Nursing|csuf? In addition, American politics were strongly divided over many controversial issues. The culture of the 1960s embraced new trends in all aspects of pop culture. Overall, the 60s was a tumultuous time of conflicting viewpoints and profound change in America’s history. Socially, many new ideas and opinions emerged in the 60s. Intern - Best Resume? The 1950s was very straight-laced.
1960s , Haight-Ashbury , Martin Luther King, Jr. 933 Words | 3 Pages. ? Introduction The 1960s was a time of Son Student, change, war, revolution, and new visions on the way the world should be. Intern - Best? The Civil rights movement . was finally seeing the transformation it’s people had been waiting for, the youth were looking for a new way of life through music, love, and the concept of peace throughout the world, and the new genre of “hippie” was born. The Kennedy’s controlled the political realm, influencing the country to become as great as it could be, and the Space Race brought about. Cold War , Hippie , Jacqueline Kennedy Onassis 3564 Words | 10 Pages. To start with, what the author discusses in the essay are the definition of fashion ,the meaning of fashion and the . interaction of this meaning with cultural values and finally he discusses the Resources Of Nursing|csuf, communication of fashion . Example [msbiodiesel.us]? Then author emphasizes the ways fashion uses to communicate and discussion of communication models that fashion uses by examining whether fashion is the meaning of an interaction between cultural values and visual culture or fashion is a reflection of an identity, a way to convey messages. Communication , Culture , Meaning of Son Student Resources Of Nursing|csuf, life 904 Words | 3 Pages. This essay is on how much the family has changed since the 1960s . This essay will contain the definitions and . variations of the family and how they have changed. There will also be details of the Ria Service Template, differences of theoretical perspectives.
There are many types of families; the most common family group is a nuclear family consisting of two adults of - School, both sexes whom are in a sexual relationship, with children either biological or adopted. They must cohabitate in the same house hold and share income. Extended family , Family , Father 1143 Words | 3 Pages. the new fashion vogues are just mere modifications and revivals of existing fashion models. Resume - Best? Topic Outline: I . Fashion Evolution A Fundamentals and Natures of Fashion B Contributing Factors of Fashion Evolution II Fashion Vogues A Fashion vogues of the old generations (1950s to 1980s) B Fashion vogues of the new generations (1990s to 2000s) III Deductions Topic- Sentence Outline: I Fashion Evolution A Fashion is delineated . 19th century , 20th century , 21st century 1905 Words | 6 Pages. How Fashion Is Seen as a Performative Art. Resources - School? | The Idea of Fashion as a Performance | Yashika Makan | This . essay refers to certain articles and talks about fashion and how it can be a performance art, and how certain components relate to Sample Word - 8+ it to enhance and back up the idea that fashion is a performative art. | Can fashion be considered as a performative art or not? In my essay I will be referring to two main sources that indicate that it can be a performative art, showing a connection. Clothing , Fashion , Kimono 1094 Words | 4 Pages.
How Does the Resources, Representation of Women Change Between 1930-1960 on the Covers of Vogue? women have changed between 1930 and 1960 and the effect Vogue has had on women’s lives. Vogue has not only contributed to Template the acceptance of . trends in the fashion and Resources - School Of Nursing|csuf beauty industry, but in addition has become a reward in the changed in cultural thinking, actions and dress of women. Vogue is the world’s most influential fashion magazine, first founded by Document Kelly Trepkowski, writing on art, culture and politics. Vogue is regularly criticized, along with the fashion industry it writes about, for Son Student Of Nursing|csuf valuing. 1930s , Conde Nast Publications , Fashion 1554 Words | 5 Pages. The emergence of anti fashion during the 1970’spromoted THE UGLY, THE CHEAP, THE ORDINARY. 7+ Sample Form Word Document Resume? Fashion trends are commonly . categorized in decades to describe the prominent designs during that particular time period. The 30’s were known as the beginning for admiration of Hollywood and the rise of glamour. (http://www.1930s-fashions.co.uk) The 60’s fashion was directed to the youth and Resources - School consisted of 7+ Sample Job Application Form Document Resume, colorful fabrics and bold designs that eradicated the formal way of dressing. Resources - School Of Nursing|csuf? (http://www.buzzle. Fashion , Haute couture , Jean-Paul Gaultier 2157 Words | 6 Pages. FASHION ‘ Fashion ’ is thus defined in the dictionary: The prevailing mode in - Part 54 such things as are subject to change in Son Student Resources - School Of Nursing|csuf form or . style, as in Word - 8+ ornament and etiquette, and especially in dress.
It is the name given to the prevailing style of living among the upper classes and the rich. Among the Son Student Resources - School Of Nursing|csuf, members of the smart set of any country, certain styles of houses, furniture, foods and drinks, times of meals, amusements, polite customs, and especially dress, are fashionable. Every person nurtures. Example Sales? Clothing , Fashion , Fashion design 1191 Words | 4 Pages. Malcolm Barnard says in his book Fashion as Communication, Fashion and clothing have always been explained as forms of . communication (39). American teenagers use fashion to communicate their feelings and beliefs. Through out Resources - School most decades teen fashion has proven to Example be a way of rebelling out how they feel and think about certain situations. They used fashion as a way of social contact with reference to scrutiny for all sorts of people.
Fashion is a communication to use to Son Student Of Nursing|csuf convey with the world. Adolescence , Afro , Clothing 1663 Words | 5 Pages. in depth discussion about fashion , its influence towards society and primarily causes responsible for these processes This . essay offers a sociological approach towards fashion in which will be critically evaluated, in context of its influence on Word Document Resume society, origins of fashion and whether external or/and internal causes are responsible for Of Nursing|csuf these processes. This essay begins with an introduction to fashion in Job Application | Farmer Resume a social aspect. According to Son Student - School Kuwamura (2005) the meaning of fashion is not just about visual. Clothing , Fashion , History of fashion design 2434 Words | 6 Pages. What Was Punk Fashion in the Early Days of the 1970s? Today everyone knows what punk fashion is, but in 1970 it didn't exist. Samples Templates - Part? . Punk first emerged in the mid 1970s in London as an anarchic and aggressive movement. About 200 young people defined themselves as an anti- fashion urban youth street culture. Closely aligned was a music movement that took the name punk. Anti Fashion - Torn Fashion Becomes Punk Fashion The clothes suited the lifestyle of those with limited cash due to unemployment and.
Body piercing , Malcolm McLaren , Nose piercing 813 Words | 3 Pages. Son Student - School? Decades: the 1960 ’s The popular trends in the 1960 . Samples Templates - Part? have changed the decade to make it in style. Trends are things such as fashion , foods, shoes, and hair. Famous fashion in the 60’s was cashmere turtle necks, colorful wide ties, Ralph Polo brands, and miniskirts (“Writers dream tools decades 60’s “ ). Amongst those people were sporting pant suits, fun furs, wet looking raincoats, pierced ears, Coco Chanel’s brand, tailored. Boston Strangler , Democratic Party , John F. Kennedy 1881 Words | 5 Pages. Time opens doors for those who know how to wait. If something should be owned by someone, it is; if not, then no matter how keen he is, it is not. This is . what we called ‘destiny’ in ancient, oriental philosophy. The essay is Resources Of Nursing|csuf targeted in Kenzo Takada (known as Kenzo), who origin from Example Of Cover Letter For Resume [msbiodiesel.us] Japan but famed in Paris. Choosing him as the target is mainly because his design is unique; the cutting is different but also not too distant, very practical, can be worn in daily life; the pattern is vivid and.
Bunka Fashion College , Fashion design , Haute couture 1873 Words | 6 Pages. joined the fashion industries and made huge contributions to the fashion career. Undeniably, the economy of a country and the . - School? fashion industries were closely related and fashion industries then became multi-billion dollar global enterprises. “The winter of 1944-5 saw the birth of Letter For Resume [msbiodiesel.us], a new, joyful era as the Son Student Of Nursing|csuf, world was free once more. Fashion enjoyed a similar liberation.” (Demornex J., 1989, p. 47) As soon as the World War II ended, the post-war economic boom began as well, the fashion industries. 1950s , Fashion , Haute couture 2088 Words | 7 Pages. ?Is fashion important? ? kaylee avery prd.1, 3/5/15 (? http://homeworktips.about.com/od/essaywriting/a/argumenttopics.htm? ) . Fashion in our times started from 1858 and had flourised over the years. The word fashion to me means simply as a way to express yourself or putting this certain thing on to boost your confidence to 7+ Sample Job Application Form Word step out in the world to feel beautiful in the inside and Resources out. To me, I believe fashion is important for three main reasons: to express yourself of how you feel. 2005 singles , Dopamine , Employment 652 Words | 2 Pages. discrimination in its field.
This essay will discuss how discrimination in Spreadsheet Example Sales Tracking Template Excel Sales education and employment has caused a major setback on the life of . minorities. There are two major dilemmas that appear throughout the Resources Of Nursing|csuf, 1960s and our current time. The first major problem is that education system is Great Templates - Part always rapidly growing in all its levels, which leads to increasingly crowded classes that can’t uphold the required material and faculty to that huge number of students, “in the 1960s public school enrollment was 1. Discrimination , Education , High school 852 Words | 3 Pages. Fashion is an underestimated social force. It functions effectively not only as an economic colossus but also to engineer social practices . Resources Of Nursing|csuf? (Finklestein). Fashion is - 8+ In Word more than its definition as a style of dress that is popular during a certain time or era.
We can learn a lot about our culture by looking at current fashion trends because they show the Son Student Resources, relationships of consumer tastes, social habits, and eras in history. If we can define the reasons behind certain fashion trends, we can analyze a. 1970s , 1980s , Clothing 1896 Words | 5 Pages. Fashion of Agreement Template, Roaring Twenties and the Sixties. Fashion of the Son Student Resources Of Nursing|csuf, Roaring Twenties and The Sixties Fashion is the style prevalent at Spreadsheet Example : Excel Sales, a given time. It usually refers to Son Student Resources - School costume . Great Samples Templates 54? or clothing style. Son Student Resources - School? Everybody has to Spreadsheet Sales Sales wear clothes, making fashion a part of everyday life. The way someone dresses says a lot about his or her personality, age, culture and experience. At times of Son Student Resources, economic or social change, fashion often changed.
The 1920s and the 1960s are big eras were economic and social change were happening. They are both largely known for their fashion. 1920s , 1960s , Flapper 1543 Words | 5 Pages. History of fashion 1900-1990 What a Difference 100 Years Makes Looking back over fashion trends for Pharmacist Intern the past 100 years can . only cause one to marvel at the drastic changes that have occurred, often in lockstep with societal changes. Women's liberation, for example, can be visually measured through the Son Student - School, evolution from suffocating corsets to jersey fabrics to bikinis. A timeline of the past century shows how the Example : Excel Sales Tracking Excel Sales, times have changed. During ancient times people wore limited clothing made from animal. Clothing , Dress , Fashion 985 Words | 3 Pages. Son Student Resources - School Of Nursing|csuf? Fashion designs come in and out of ‘style’, which is known as the cycle of fashion . Trends always come in and out of style, but . the consumers keep up with trends due to the feeling of needing the Job Application | Farmer, newest trend.
Fashion is fuelled by conversion. Designers continually persuade the Son Student - School Of Nursing|csuf, public that their new ideas are everything that a stylish wardrobe requires. 7+ Sample Job Application Form Resume? In upcoming seasons, the same designers convince everyone to give up their now outdated designs and embrace the Son Student Resources Of Nursing|csuf, trends of the Template 408(b)(2), latest collections. Clothing , Fashion , Jeans 1440 Words | 4 Pages. Global Essay Oppressive Clothing March 2011 Women have been faced with many challenges throughout history. A major example of this would . Resources Of Nursing|csuf? be the fight for women’s rights and Job Application Word | Farmer Resume equality. Women worked and worked to Son Student Resources - School Of Nursing|csuf attempt to gain equality with men and Sample Word In Word eventually triumphed.
However, another challenge that women had to face was oppressive clothing and fashion . Resources - School? The corset, the practice of foot binding, and hijabs were all massive parts of oppressive fashion . Each served a specific purpose, but hindered. 19th century , Clothing , Foot 1060 Words | 3 Pages. ‘‘ Fashion provides one of the most ready means through which individuals can make expressive visual statements about their identities’’. . Tracking? Bennet, A. (2005). Culture and Everyday Life. Resources? London: Sage. p. Samples Templates - Part 54? 96. Discuss this statement with reference to individual examples. Son Student Of Nursing|csuf? As Bennet suggests in the above statement, People use fashion as one of the easiest and 7+ Sample Form Word Document realistic ways in which they can express their personality and their true identity to show to others in Resources Of Nursing|csuf their everyday life to show their. Letter? Clothing , Fashion , Female 2150 Words | 6 Pages. is culturally literate. Second, being literate can mean having knowledge or competence. For example, we speak of people being computer literate or . Son Student? politically literate. For your first essay , try to Microsoft Word In Word focus on a moment or a period in your life when you realized the significance of being literate in - School Of Nursing|csuf this fashion . Did you have trouble using a computer to 7+ Sample Job Application Form Word Document Resume register for classes? Did you fit into a subculture because you learned to speak its slang?
Did a special skill or aptitude you possess have a profound. Essay , Knowledge , Literacy 1120 Words | 4 Pages. predictions on the future of the Son Student Resources Of Nursing|csuf, world fashion industry 20 years from Word - 8+ Examples In Word now.” Essay Joris Rotsaert M2Ei . ___________________________________________________________________ So, according to Son Student Resources - School Of Nursing|csuf an ancient prediction of the Maya’s, the world is going down in 2012. But best case scenario: we will still be here 20 years from now, how will that world look like, How will fashion look like in 20 years from now? In my opinion the future of Letter For Resume [msbiodiesel.us], fashion and the earth in general will be more efficient. Clothing , Earth , Fashion 2146 Words | 5 Pages. ? The Hero in Lyrics and Fashion The character of the lyric, “No Such Thing” by John Mayer, is Son Student Resources - School a confident individual who is striving to . be different from the majority whom abandoned individuality. The character shows his confidence by stating, “I’d like to think the best of me.” His statement displays that other people’s opinions do not startle him.
The line, “They love to Microsoft Examples tell you stay inside the lines,” criticizes the Son Student Resources, society’s standard which forces the majority of Template 408(b)(2), people to abandon their. Blue , Clothing , Collar 694 Words | 2 Pages. Surrealism In Fashion Essay Surrealism Surrealism in Fashion Symbolism and Metaphors -Human Form and Parts . -Displacement of Objects -Nature and Son Student Fantasy Surrealism in the Fashion Industry -Case Study 1: Elsa Schiaparelli -Case Study 2: Viktor Rolf The Lasting Impact of Surrealism on 7+ Sample Word Document | Farmer Resume Fashion Conclusion http://www.ukessays.com/ essays / fashion /exploring-surrealism-in- fashion - fashion -essay.php Read more: http://www.ukessays.com/ essays / fashion /exploring-surrealism-in- fashion - fashion -essay.php#ixzz2OTzqx8P0 . Andre Breton , Anti-art , Avant-garde 968 Words | 4 Pages. FASHION IN THE COLD WAR By Imani Jones Analyze how and Resources Of Nursing|csuf why the cold war affected both sides’ fashion styles. . The Cold War traumatically affected the Samples Templates - Part 54, lifestyles of the United States, Soviet Union, China and Europe; however, the Cold War played a major role in fashion history. Fashion during the Cold War gave people the opportunity to express themselves through what they wore. Son Student Resources - School? Due to Communism in other countries such as China, people were neither able to wear what they wanted. Cold War , Communism , Communist state 2187 Words | 6 Pages.
Fashion Photography Fashion has always been a mirrored image of the collective consciousness and unconsciousness of Agreement, society. . In politically conservative times, fashion reflects the staidness of the majority, however additionally the Son Student Resources - School, subversive parts of the minority. No less a controversial figure than King Louis XIV of France was rumoured to have said that fashion was a mirror. Music, films, and TV, all potent popular culture mirrors in their own right of the anxieties, hopes, and Example : Excel Excel dreams of. Fashion magazines , Fashion photographers , Fashion photography 1933 Words | 6 Pages. English 101 April 5, 2007 Writer’s Checklist for Cause and Effect Essay 1. Have I identified the cause or effect I am analyzing in my . thesis? The cause: How fashion is - School affected by the media and other sources.
The effect: How fashion effects a person in Great Samples - Part today’s society. 2. Have I explained the cause-and-effect relationship convincingly? Throughout the course of the Son Student - School Of Nursing|csuf, essay I explain how media causes the fads and fashion to change, as well as how these changes can affect the possibility of Ria Service Template 408(b)(2), getting. Causality , Effect , Essay 826 Words | 3 Pages. ? Fashion throughout the Decades Interest: I chose to Son Student Resources - School Of Nursing|csuf look at fashion and how it has changed and developed through the decades. Pharmacist Intern Resume? . Fashion up until the 1960 ’s varied widely. The 1960 ’s specifically were known as the “Flower Power” era, or the hippie movement. Son Student Of Nursing|csuf? One of the social youth groups preceding the Sample Examples, Flower Power era was referred to as the rockers.
The rockers were a group of younger generations who typically wore black clothing such as leather jackets. Their style is echoed in greatly in the idea. 1980s fashion , 1990s fashion , Bell-bottoms 853 Words | 3 Pages. Almonte J.K. Offerman FMM 114 Museum Trip Visit 1920s The 1920s represented a time of tremendous social change, which was reflected in . fashion as well. For women, short bobs because fashionable as did shorter skirts such as pinafores that would never have been allowed in previous decades.
There was a certain androgynous look to women's fashion that borrowed from men's clothing liberally. Forward thinking designers like Coco Chanel and Jean Patou made sportswear fashionable as well. Clothing , Coco Chanel , Denim 1445 Words | 5 Pages. The Evolution of American Women's Fashion. Son Student Resources - School? The Evolution of American Women's Fashion Motto: “ Fashion is not something that exists in dresses only.
Fashion is . in the sky, in the street; fashion has to do with ideas, the way we live, what is happening.” (Coco Chanel) Fashion has always been a reflection of the collective consciousness and unconsciousness of society. Spreadsheet : Excel Sales Template Excel Sales? Indeed, until recent centuries, it was the concern of the aristocracy; the clothing of Son Student - School, ordinary people changed far less radically. However, the old time consuming traditions. 19th century , 20th century , Clothing 1829 Words | 5 Pages. Skirt still in fashion ? Is Mini Skirt still in fashion ? Fashion in Ria Service Agreement Template 1950 – 70 era Is Mini Skirt still in . Son Student Resources Of Nursing|csuf? fashion ? Today we are in the 21st century in an era where the fashion is at its peak.
The fashion industry has developed so fast during the last decade. Pharmacist Intern? This is mainly due to the development of technology. The Mini Skirt emerged during the late 1950 amp; was very popular between 1950 to Of Nursing|csuf 1970 20th century can be named as the Example Of Cover [msbiodiesel.us], era where there was a significant development of the fashion industry. During. Fashion , Hemline , Mary Quant 2096 Words | 6 Pages. There will be two long (30-minute) essays on the College Board AP Art History Exam. In each case, you will have to compare two works of art of . your own choosing. Son Student - School Of Nursing|csuf? One essay will require that you include an artwork from outside the European tradition in Ria Service Agreement your selection. Choosing Works to Compare. It is important to select appropriate works that will allow for Son Student - School thoughtful comparison and contrast.
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Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack. Yongjun Wang, M.D., Yilong Wang, M.D., Ph.D., Xingquan Zhao, M.D., Ph.D., Liping Liu, M.D., Ph.D., David Wang, D.O., F.A.H.A., F.A.A.N., Chunxue Wang, M.D., Ph.D., Chen Wang, M.D., Hao Li, Ph.D., Xia Meng, M.D., Ph.D., Liying Cui, M.D., Ph.D., Jianping Jia, M.D., Ph.D., Qiang Dong, M.D., Ph.D., Anding Xu, M.D., Ph.D., Jinsheng Zeng, M.D., Ph.D., Yansheng Li, M.D., Ph.D., Zhimin Wang, M.D., Haiqin Xia, M.D., and S. Claiborne Johnston, M.D., Ph.D., for the CHANCE Investigators * N Engl J Med 2013; 369:11-19 July 4, 2013 DOI: 10.1056/NEJMoa1215340. Comments open through July 10, 2013. Stroke is Son Student - School Of Nursing|csuf, common during the Job Application Form Word Document Resume, first few weeks after a transient ischemic attack (TIA) or minor ischemic stroke. Combination therapy with clopidogrel and aspirin may provide greater protection against subsequent stroke than aspirin alone. In a randomized, double-blind, placebo-controlled trial conducted at 114 centers in China, we randomly assigned 5170 patients within 24 hours after the onset of minor ischemic stroke or high-risk TIA to combination therapy with clopidogrel and aspirin (clopidogrel at an initial dose of 300 mg, followed by 75 mg per Son Student Resources - School day for 90 days, plus aspirin at a dose of 75 mg per day for Ria Service Agreement Template, the first 21 days) or to placebo plus aspirin (75 mg per day for 90 days).
All participants received open-label aspirin at a clinician-determined dose of 75 to Son Student Of Nursing|csuf, 300 mg on day 1. The primary outcome was stroke (ischemic or hemorrhagic) during 90 days of follow-up in an intention-to-treat analysis. Treatment differences were assessed with the Ria Service 408(b)(2), use of a Cox proportional-hazards model, with study center as a random effect. Stroke occurred in Resources 8.2% of patients in the clopidogrel–aspirin group, as compared with 11.7% of those in Microsoft - 8+ Examples the aspirin group (hazard ratio, 0.68; 95% confidence interval, 0.57 to 0.81; P0.001). Moderate or severe hemorrhage occurred in seven patients (0.3%) in Son Student the clopidogrel–aspirin group and in eight (0.3%) in the aspirin group (P=0.73); the rate of hemorrhagic stroke was 0.3% in each group. Among patients with TIA or minor stroke who can be treated within 24 hours after the onset of symptoms, the : Excel Sales Sales, combination of - School Of Nursing|csuf clopidogrel and aspirin is Spreadsheet Sales Sales, superior to aspirin alone for reducing the Son Student Resources, risk of stroke in Agreement the first 90 days and does not increase the risk of Resources Of Nursing|csuf hemorrhage. Great Samples? (Funded by the Ministry of Science and Technology of the Resources Of Nursing|csuf, People's Republic of China; CHANCE ClinicalTrials.gov number, NCT00979589.) Transient ischemic attack (TIA) and acute minor ischemic stroke are common and often lead to disabling events. In China, there are approximately 3 million new strokes every year, and approximately 30% of Spreadsheet Example : Excel Sales Template them are minor ischemic strokes. 1,2 The incidence of TIA in China has not been determined, but on the basis of the incidence in other countries, there are probably more than 2 million TIAs annually in China. 3-5 The risk of another stroke occurring after a TIA or minor stroke is high, with approximately 10 to - School, 20% of Pharmacist Intern Resume Example patients having a stroke within 3 months after the Son Student - School, index event; most of these strokes occur within the first 2 days. 5-8. The role of Great Samples - Part 54 antiplatelet therapy for secondary stroke prevention has been well established.
However, aspirin is the only antiplatelet agent that has been studied in the acute phase of stroke, during which its benefit is modest. 9,10 Aspirin and Son Student Resources Of Nursing|csuf clopidogrel synergistically inhibit platelet aggregation, 11,12 and such dual therapy reduces the risk of recurrent ischemic events in patients with the acute coronary syndrome. 13,14 Large-scale trials of secondary prevention of ischemic events after stroke have not shown a benefit of the Samples - Part, combination of clopidogrel and aspirin. 15-17 However, these trials did not study the early, high-risk period after stroke, they included some patients with strokes of moderate severity, and Son Student Resources - School Of Nursing|csuf they included few if any patients with TIA. Three small pilot trials have shown trends toward a benefit of the Of Cover For Resume, combination therapy and minimal safety concerns in patients with minor stroke or TIA. Resources? 18-20. We conducted the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial to test the hypothesis that 3 months of treatment with a combination of Great Templates - Part clopidogrel and aspirin would reduce the risk of recurrent stroke, as compared with aspirin alone, among patients with acute high-risk TIA or minor ischemic stroke. We conducted this study according to the protocol and statistical analysis plan, which are available with the full text of Son Student this article at NEJM.org. The trial was designed by three of the authors and was overseen by the executive committee, which had full access to the data. Data collection and entry were performed by staff at the Tiantan Clinical Trial and Research Center for Stroke, where the Spreadsheet Example : Excel Tracking Template, data analysis was performed. One of the Son Student, authors had full access to Pharmacist - Best, an independent database for Son Student, any questions regarding the analyses.
All members of the Job Application, writing committee contributed to and approved an - School Of Nursing|csuf earlier draft of this manuscript, which was prepared without professional editorial assistance. The first and last authors made the decision to submit the manuscript for publication. All the authors assume responsibility for Pharmacist Intern Resume, the accuracy and Resources - School Of Nursing|csuf completeness of the Great - Part 54, data and Son Student Resources - School the fidelity of this report to the study protocol. There was no confidentiality agreement between the study sponsor (the Ministry of Science and Technology of the People's Republic of China) and the investigators. There was no commercial support for this study. All the participants or their legal proxies provided written informed consent. Form Document | Farmer? The CHANCE protocol was approved by the ethics committee at Son Student, each study center. Clopidogrel and the matching placebo were purchased from Sanofi-Aventis, which had no other role in Microsoft Word - 8+ the study. Patients who met the following inclusion criteria were eligible: age of 40 years or older; diagnosis of an Son Student Resources acute minor ischemic stroke or TIA; and ability to start the study drug within 24 hours after symptom onset, which was defined as the point at which the Ria Service 408(b)(2), patient reported no longer being in Of Nursing|csuf a normal condition. Acute minor stroke was defined by a score of 3 or less at the time of randomization on the National Institutes of Health Stroke Scale (NIHSS; scores range from 0 to 42, with higher scores indicating greater deficits). TIA was defined as focal brain ischemia with resolution of symptoms within 24 hours after onset plus a moderate-to-high risk of stroke recurrence (defined as a score of ?4 at the time of randomization on the ABCD, 2 which assesses the risk of stroke on the basis of age, blood pressure, clinical features, duration of Agreement Template TIA, and Son Student Resources Of Nursing|csuf presence or absence of diabetes; scores range from 0 to 7, with higher scores indicating greater short-term risk).
All patients with possible clinical neurologic events during the follow-up period underwent computed tomography (CT) or magnetic resonance imaging (MRI) of the head. Resume? Patients were excluded if they had any of the following: hemorrhage; other conditions, such as vascular malformation, tumor, abscess, or other major nonischemic brain disease; isolated sensory symptoms (e.g., numbness), isolated visual changes, or isolated dizziness or vertigo without evidence of acute infarction on baseline CT or MRI of the head; a score of more than 2 on the modified Rankin scale (scores range from 0 [no symptoms] to 6 [death]) immediately before the Resources Of Nursing|csuf, occurrence of the index ischemic stroke or TIA, indicating moderate disability or worse at baseline; an Sales NIHSS score of 4 or more at - School Of Nursing|csuf, randomization; a clear indication for anticoagulation therapy (presumed cardiac source of 7+ Sample Job Application | Farmer embolus, such as atrial fibrillation or prosthetic cardiac valve) or a contraindication to clopidogrel or aspirin; history of intracranial hemorrhage; anticipated requirement for long-term nonstudy antiplatelet drugs or for nonsteroidal antiinflammatory drugs affecting platelet function; heparin therapy or oral anticoagulation therapy within 10 days before randomization; gastrointestinal bleeding or major surgery within the previous 3 months; planned or probable revascularization (any angioplasty or vascular surgery) within 3 months after screening (if clinically indicated, vascular imaging was to - School Of Nursing|csuf, be performed before randomization, whenever possible); planned surgery or interventional treatment requiring cessation of the study drug; TIA or minor stroke caused by angiography or surgery; or severe noncardiovascular coexisting condition, with a life expectancy of less than 3 months. Women of childbearing age who were not practicing reliable contraception and did not have a documented negative pregnancy test and patients receiving other investigational drugs or devices were also excluded (see Table S1 in Samples Templates 54 the Supplementary Appendix, available at NEJM.org). No patients included in the study were treated with thrombolysis around the time of randomization. CHANCE was a randomized, double-blind, placebo-controlled clinical trial conducted at - School Of Nursing|csuf, 114 clinical centers in China; details of the rationale for the study and its design have been published previously. 21 Patients meeting the enrollment criteria were randomly assigned to one of the two treatment groups with the use of a double-blind, double-dummy design. The site investigator called into an automated system that randomly assigned a number corresponding to Spreadsheet Tracking Template Excel, a medication kit stored at the study site, and the medication in the kit was administered to the patient.
Both groups received open-label aspirin on day 1 (with the dose ranging from 75 to 300 mg, at the discretion of the treating physician). Patients randomly assigned to the clopidogrel–aspirin group received a loading dose of 300 mg of clopidogrel on day 1, followed by a dose of 75 mg per day on days 2 through 90, aspirin at a dose of 75 mg per day on days 2 through 21, and placebo aspirin on days 22 through 90. - School Of Nursing|csuf? Patients randomly assigned to the aspirin group received a placebo version of clopidogrel on days 1 through 90 and aspirin at a dose of 75 mg per Example : Excel Tracking Template Sales day on days 2 through 90. Randomization was stratified according to clinical center and interval between symptom onset and enrollment (12 hours vs. Son Student - School? 12 to 24 hours). The primary objective was to Job Application Word Resume, assess the effects of the two treatment regimens on the incidence of stroke in the first 90 days after acute minor stroke or high-risk TIA. The primary efficacy outcome was a new stroke event (ischemic or hemorrhagic) at 90 days. Ischemic stroke was defined as an acute focal infarction of the brain or retina with one of the following: sudden onset of a new focal neurologic deficit, with clinical or imaging evidence of infarction lasting 24 hours or more and not attributable to a nonischemic cause (i.e., not associated with brain infection, trauma, tumor, seizure, severe metabolic disease, or degenerative neurologic disease); a new focal neurologic deficit lasting for Son Student Resources Of Nursing|csuf, less than 24 hours and Agreement 408(b)(2) not attributable to a nonischemic cause but accompanied by neuroimaging evidence of new brain infarction; or rapid worsening of an existing focal neurologic deficit lasting more than 24 hours and not attributable to a nonischemic cause, accompanied by new ischemic changes on MRI or CT of the brain and clearly distinct from the index ischemic event. Hemorrhagic stroke was defined as acute extravasation of blood into the brain parenchyma or subarachnoid space with associated neurologic symptoms. Recurrent stroke was considered to be disabling if the score on the modified Rankin scale was 2 or more.
The primary safety outcome was a moderate-to-severe bleeding event, according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO) definition. 22 Severe hemorrhage was defined as fatal or intracranial hemorrhage or other hemorrhage causing hemodynamic compromise that required blood or fluid replacement, inotropic support, or surgical intervention. Moderate hemorrhage was defined as bleeding that required transfusion of blood but did not lead to hemodynamic compromise requiring intervention. 22. Key secondary efficacy outcomes included a new clinical vascular event (ischemic stroke, hemorrhagic stroke, myocardial infarction, or vascular death), analyzed as a composite outcome and also as individual outcomes. Vascular death was defined as death due to stroke (ischemic or hemorrhagic), systemic hemorrhage, myocardial infarction, congestive heart failure, pulmonary embolism, sudden death, or arrhythmia.
Efficacy outcomes were also analyzed according to prespecified subgroups. All reported efficacy and safety outcomes were confirmed by a central adjudication committee that was unaware of the Of Nursing|csuf, study-group assignments. The committee members classified ischemic-stroke subtypes on the basis of available diagnostic studies. Example? A data and safety monitoring board whose members were selected by the sponsor was in place to Resources, ensure the safety of patients during the Ria Service, study, with predetermined periodic assessments of safety and Resources stopping rules. We calculated that a sample of 408(b)(2) 5100 patients would provide 90% power to detect a relative risk reduction of 22% in the clopidogrel–aspirin group, with a two-sided type I error of 0.05, assuming an Son Student Resources - School event rate of 14% in the aspirin group and a 5% overall rate of withdrawal (defined as medication nonadherence). 21. No patient withdrew between the 7+ Sample Word Document Resume, time of randomization and the administration of the first dose of study medication; all analyses were based on the population of patients who underwent randomization. We compared the - School, baseline characteristics of the patients in Agreement 408(b)(2) the two study groups.
Proportions were used for categorical variables, and Son Student Resources - School Of Nursing|csuf medians with interquartile ranges were used for continuous variables. Form Word Resume? Time to Son Student Resources - School Of Nursing|csuf, randomization was calculated as a group mean. Differences between study groups in In Word the rate of stroke (ischemic or hemorrhagic) during the 90-day follow-up period were assessed with the use of a Cox proportional-hazards model, with pooled study centers (?20 patients) as a random effect. Hazard ratios with 95% confidence intervals are reported. When there were multiple events of the same type, the time to the first event was used in the model. Data from patients who had no events during the study were censored at the time of - School study termination or death. We used this approach to maximize the time-dependent information in 7+ Sample Word the trial while maintaining the ease of Resources - School interpretation of risks. For each model, the proportional-hazards assumption was assessed by testing the Great Templates - Part 54, interaction between treatment and time. In addition, we assessed whether the treatment effect differed in certain prespecified subgroups by testing the treatment-by-subgroup interaction effect with the use of Cox models.
All tests were two-sided, and a P value of 0.05 was considered to indicate statistical significance. All statistical analyses were performed with the use of SAS software, version 9.0 (SAS Institute). Between October 2009 and July 2012, a total of Son Student 41,561 patients with stroke or TIA were screened at 114 clinical sites; 5170 patients were enrolled, with 2584 randomly assigned to the clopidogrel–aspirin group and Spreadsheet Tracking Template Sales 2586 to - School Of Nursing|csuf, the aspirin group. The most common reasons for exclusion were delayed presentation (26.4% of screened patients); moderate or severe stroke (10.4%); intracranial hemorrhage (7.0%); low-risk TIA, defined as a score of 4 on the ABCD 2 (6.5%); or contraindication to clopidogrel or aspirin (6.0%) (Fig. S3 in the Supplementary Appendix). The two groups were well balanced regarding baseline characteristics ( Table 1 Table 1 Baseline Characteristics of the 7+ Sample Job Application Form | Farmer, Patients. ). The median age was 62 years, and 33.8% of the patients were women. Son Student - School? A total of 65.7% of the patients had a history of hypertension, 21.1% had diabetes, and 43.0% were current or former smokers. The median time from the Example Of Cover Letter For Resume, onset of the qualifying minor stroke or TIA to Resources Of Nursing|csuf, randomization was 13 hours. The index event was a TIA in 1445 patients (27.9%).
A total of 36 patients (0.7%) — 20 in the clopidogrel–aspirin group and 16 in the aspirin group — were lost to follow-up; 165 patients (6.4%) in Agreement 408(b)(2) the clopidogrel–aspirin group and 146 (5.6%) in the aspirin group discontinued the study medication before the end of the study (Fig. Resources? S3 in the Supplementary Appendix). Stroke occurred in 212 patients (8.2%) in the clopidogrel–aspirin group, as compared with 303 patients (11.7%) in the aspirin group (hazard ratio, 0.68; 95% confidence interval [CI], 0.57 to 0.81; P0.001) ( Table 2 Table 2 Efficacy and Safety Outcomes. and Figure 1 Figure 1 Probability of Survival Free of Stroke. The primary outcome was ischemic or hemorrhagic stroke. The inset shows the same data on an enlarged segment of the y axis. Spreadsheet Example Sales? ). Resources Of Nursing|csuf? Fatal or disabling stroke occurred in 135 patients (5.2%) in the clopidogrel–aspirin group and in 177 (6.8%) in the aspirin group (hazard ratio, 0.75; 95% CI, 0.60 to 0.94; P=0.01). Ischemic stroke occurred in 204 patients (7.9%) in Letter [msbiodiesel.us] the clopidogrel–aspirin group and in 295 (11.4%) in the aspirin group (hazard ratio, 0.67; 95% CI, 0.56 to 0.81; P0.001). Hemorrhagic stroke occurred in Resources 8 patients in each of the two study groups (0.3% of each group). Key Secondary and Other Efficacy Outcomes. The composite outcome of vascular events occurred in 216 patients (8.4%) in the clopidogrel–aspirin group, as compared with 307 patients (11.9%) in Spreadsheet Template Sales the aspirin group (hazard ratio, 0.69; 95% CI, 0.58 to 0.82; P0.001) ( Table 2 , and Fig. S4 in the Supplementary Appendix).
Death from Of Nursing|csuf any cause occurred in 0.4% of the patients in each group. Vascular death (including death from Agreement hemorrhagic stroke) occurred in 6 patients (0.2%) in the clopidogrel–aspirin group and in 5 (0.2%) in Resources the aspirin group. TIA occurred in 39 patients (1.5%) in Template 408(b)(2) the clopidogrel–aspirin group and in 47 (1.8%) in the aspirin group (P=0.36). Moderate or severe hemorrhage, as defined by means of the Son Student Resources Of Nursing|csuf, GUSTO criteria, occurred in seven patients (0.3%) in the clopidogrel–aspirin group and in eight (0.3%) in the aspirin group (P=0.73) ( Table 2 ). The rate of any bleeding event was 2.3% in the clopidogrel–aspirin group as compared with 1.6% in the aspirin group (hazard ratio, 1.41; 95% CI, 0.95 to 2.10; P=0.09) ( Table 2 ). The reduction in the rate of stroke and combined secondary vascular events with clopidogrel and aspirin was consistent across all major subgroups ( Figure 2 Figure 2 Hazard Ratio for 408(b)(2), the Primary Outcome in Son Student Of Nursing|csuf Prespecified Subgroups. The reduction in Job Application Form the risk of stroke with clopidogrel and Son Student - School aspirin, as compared with aspirin alone, was consistent across all major subgroups. Pharmacist Resume - Best Resume Example? There were no significant interactions in any of the 11 predefined subgroups (P0.10 for Resources Of Nursing|csuf, all comparisons). Data on systolic blood pressure at baseline were missing for 4 patients. The ABCD 2 assesses the risk of stroke on the basis of age, blood pressure, clinical features, duration of transient ischemic attack (TIA), and presence or absence of diabetes, with scores ranging from 0 to 7 and Spreadsheet Tracking Sales higher scores indicating greater short-term risk. , and Fig. Son Student Of Nursing|csuf? S5 in the Supplementary Appendix). There were no significant interactions in any of the 11 predefined subgroups (P0.10 for all comparisons).
Adverse events occurred in similar proportions of patients in Ria Service Agreement 408(b)(2) the two groups (5.8% in the clopidogrel–aspirin group and 5.0% in - School Of Nursing|csuf the aspirin group). The proportions of Job Application Form Resume patients with serious adverse events were also similar (1.0% and 0.8% in the clopidogrel–aspirin and aspirin groups, respectively) (Table S4 in the Supplementary Appendix). In this large-scale trial involving patients with high-risk TIA or minor ischemic stroke, we found that the - School Of Nursing|csuf, addition of clopidogrel to aspirin within 24 hours after symptom onset reduced the risk of subsequent stroke by 32.0%, as compared with aspirin alone. Event rates during this early period were very high, and clopidogrel was associated with an absolute risk reduction of Templates - Part 54 3.5 percentage points, equivalent to a number needed to Son Student Resources - School Of Nursing|csuf, treat of 29 patients to prevent one stroke over a period of 90 days. Combination therapy with clopidogrel and Letter [msbiodiesel.us] aspirin, as compared with aspirin alone, was not associated with an increased incidence of hemorrhage, although there was a worrisome trend in overall bleeding toward more events with the combination therapy.
The results of our trial differ from Resources - School Of Nursing|csuf those of 7+ Sample Job Application Form Document | Farmer Resume other trials of - School Of Nursing|csuf combination therapy with clopidogrel and aspirin after cerebral ischemic events. 7,8,17 One possible explanation is that, unlike previous trials, our trial targeted a population at particularly high risk for recurrent ischemia and at low risk for hemorrhage. Previous trials included patients with more severe strokes than our trial did, and they did not enroll patients in the first hours after an index minor stroke or TIA, during which the risk of Of Cover For Resume recurrent ischemia is particularly high. This may explain why other trials did not show a reduction in the risk of ischemic events but did show an increased risk of hemorrhage. In our study, the Of Nursing|csuf, curves for Pharmacist Intern Resume - Best Resume Example, survival free of stroke were particularly steep in Son Student - School the first few days, during which the curves representing the treatment groups diverged dramatically. Example Of Cover Letter [msbiodiesel.us]? Subsequently, the Resources, rates of stroke were similar. This suggests that the requirement for randomization within 24 hours after the onset of symptoms, with nearly half the patients enrolled within 12 hours (and treated shortly thereafter), was important.
Although we did not see a relative difference in the efficacy outcome between patients randomly assigned to a study group within 12 hours and Word | Farmer Resume those assigned after a longer interval, absolute event rates were higher among those who were enrolled within 12 hours. Son Student Resources? In clinical practice, treatment with clopidogrel and Example Of Cover Letter For Resume [msbiodiesel.us] aspirin as soon as possible after symptom onset is likely to produce the Son Student Resources - School, greatest absolute benefit, since ischemic event rates are highest in Templates - Part the initial hours after symptoms appear. Our trial was conducted entirely in Resources - School China, a country with approximately 150 to 250 deaths from stroke per 100,000 persons per year, which is five times as high as the rate in the United States. 23 Although diagnostic tools and therapies commonly used in the United States and Europe are available in most hospitals in China, some patients cannot afford this level of care. 24,25 Secondary prevention practices are also less rigorous in China, where rates of treatment of hypertension, diabetes, and hyperlipidemia are low, as shown in our study population (Table S3 in the Supplementary Appendix). Furthermore, the 7+ Sample Job Application | Farmer, distribution of stroke subtypes in China differs from that in more developed countries; China has a higher incidence of large-artery intracranial atherosclerosis 25 and a higher prevalence of genetic polymorphisms that affect the metabolism of clopidogrel.
26 The Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) trial (ClinicalTrials.gov number, NCT00991029), sponsored by the National Institutes of Health, which is similar to our trial, is now enrolling patients at Son Student Resources Of Nursing|csuf, sites primarily in the United States. 27 The POINT trial is assessing a higher loading dose of clopidogrel (600 mg) and a narrower time window (treatment within 12 hours after symptom onset) than were used in our study. Several common clinical conditions mimic TIA, including seizures, migraine, peripheral vertigo, syncope, and anxiety. 28 To minimize the risk of enrolling patients with TIA mimics, we excluded all patients with isolated sensory symptoms, isolated visual changes, or isolated dizziness or vertigo without evidence of acute infarction on baseline CT or MRI of the : Excel Sales Sales, head. In addition, enrollment of Son Student patients with TIA was limited to those with a high ABCD 2 score (?4) to Pharmacist Intern Example, increase the Resources Of Nursing|csuf, likelihood that spells were due to true TIAs and to - 8+, ensure that we were enrolling patients who were at high risk for - School Of Nursing|csuf, subsequent ischemic events. Pharmacist Resume? 29 The risk of subsequent stroke in the trial was high for this patient population, suggesting that our strategy was successful. Our findings may not apply to other populations of patients with ischemic events.
In conclusion, our study shows that among patients with high-risk TIA or minor ischemic stroke who are initially seen within 24 hours after symptom onset, treatment with clopidogrel plus aspirin for 21 days, followed by clopidogrel alone for a total of 90 days, is Son Student Resources Of Nursing|csuf, superior to aspirin alone in reducing the risk of subsequent stroke events. The combination of clopidogrel with aspirin did not cause more hemorrhagic events in this patient population than aspirin alone. Supported by grants (2008ZX09312-008, 2011BAI08B02, 2012ZX09303, and Template 408(b)(2) 200902004) from the Ministry of Science and Son Student - School Technology of the People's Republic of Job Application Document Resume China. Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. No potential conflict of Resources - School interest relevant to this article was reported. This article was published on June 26, 2013, at NEJM.org. From Beijing Tiantan Hospital (Yongjun Wang, Yilong Wang, X.Z., L.L., Chunxue Wang, Chen Wang, H.L., X.M.) and Xuan Wu Hospital (J.J.), Capital Medical University, and Peking Union Medical College Hospital (L.C.), Beijing; Huashan Hospital of Great 54 Fudan University (Q.D.) and Renji Hospital of Shanghai Jiaotong University (Y.L.), Shanghai; First Affiliated Hospital of Jinan University (A.X.) and First Affiliated Hospital of Resources Sun Yat-Sen University (J.Z.), Guangzhou; Taizhou First People's Hospital, Taizhou (Z.W.); and Intern Resume - Best Resume Example Taiyuan Iron and Son Student Steel Group, General Hospital, Taiyuan (H.X.) — all in China; Illinois Neurological Institute Stroke Network, Sisters of the Third Order of St. Francis Healthcare System, University of Illinois College of Medicine, Peoria (D.W.); and the Departments of Neurology and Epidemiology, University of California, San Francisco, San Francisco (S.C.J.).
Address reprint requests to Dr. Yongjun Wang at No. 6 Tiantanxili, Dongcheng District, Beijing 100050, China, or at Sales Template Sales, [email protected]; or to Dr. Johnston at the Departments of Son Student Resources - School Neurology and Epidemiology, University of California, 505 Parnassus Ave., M-798, San Francisco, CA 94143-0114, or at 7+ Sample Job Application Form Word Document | Farmer Resume, [email protected] A complete list of investigators and institutions participating in the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial is provided in the Supplementary Appendix, available at NEJM.org. Zhao D , Liu J , Wang W , et al. Son Student Of Nursing|csuf? Epidemiological transition of Spreadsheet : Excel Sales Template stroke in China: twenty-one-year observational study from the Sino-MONICA-Beijing Project. Stroke 2008;39:1668-1674. Wang YL , Wu D , Liao X , Zhang W , Zhao X , Wang YJ . Burden of stroke in China.
Int J Stroke 2007;2:211-213. Johnston SC , Fayad PB , Gorelick PB , et al. Prevalence and knowledge of transient ischemic attack among US adults. Neurology 2003;60:1429-1434. Edlow JA , Kim S , Pelletier AJ , Camargo CA Jr . Resources - School? National study on emergency department visits for transient ischemic attack, 1992-2001. Acad Emerg Med 2006;13:666-672. Kleindorfer D , Panagos P , Pancioli A , et al.
Incidence and short-term prognosis of transient ischemic attack in a population-based study. Stroke 2005;36:720-723. Coull AJ , Lovett JK , Rothwell PM . Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and Example [msbiodiesel.us] organisation of Son Student Resources - School services. BMJ 2004;328:326-326. Johnston SC , Gress DR , Browner WS , Sidney S . Short-term prognosis after emergency department diagnosis of TIA. JAMA 2000;284:2901-2906. Lovett JK , Coull AJ , Rothwell PM . Samples - Part 54? Early risk of recurrence by Of Nursing|csuf, subtype of Job Application Form Word Resume ischemic stroke in Son Student - School population-based incidence studies. Neurology 2004;62:569-573. CAST (Chinese Acute Stroke Trial) Collaborative Group . CAST: randomised placebo-controlled trial of early aspirin use in Agreement 20,000 patients with acute ischaemic stroke. Lancet 1997;349:1641-1649.
The International Stroke Trial (IST): a randomised trial of Son Student - School aspirin, subcutaneous heparin, both, or neither among 19 435 patients with acute ischaemic stroke. Lancet 1997;349:1569-1581. Herbert JM , Dol F , Bernat A , Falotico R , Lale A , Savi P . The antiaggregating and antithrombotic activity of clopidogrel is Intern - Best Resume Example, potentiated by aspirin in several experimental models in the rabbit. Thromb Haemost 1998;80:512-518. Makkar RR , Eigler NL , Kaul S , et al. Effects of clopidogrel, aspirin and Resources combined therapy in a porcine ex vivo model of Great Templates - Part 54 high-shear induced stent thrombosis. Eur Heart J 1998;19:1538-1546. Yusuf S , Zhao F , Mehta SR , Chrolavicius S , Tognoni G , Fox KK . Effects of clopidogrel in addition to Resources - School, aspirin in Sample Word - 8+ Examples patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345:494-502[Erratum, N Engl J Med 2001;345:1506, 1716.] Steinhubl SR , Berger PB , Mann JT III , et al. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial.
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